New Research Shows Sleep Duration Impacts Microvascular Disease in Newly Diagnosed Diabetes Patients
Introduction
New research to be presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Madrid from September 9 to 13, 2019, reveals a correlation between sleep duration and microvascular disease in individuals newly diagnosed with type 2 diabetes. A team of researchers, led by Mette Johansen and Thomas Olesen from the Steno Diabetes Center Odense at the Odense University Hospital in Denmark, conducted a study to explore this association.
The Study
The researchers studied the sleep patterns of 396 newly diagnosed type 2 diabetes patients over a ten-day period using Axivity AX3 accelerometers. They classified the participants’ sleep duration at night into three categories: short (<7 hours), optimal (7 to <9 hours), and long (9 hours or more). Microvascular disease was defined as either a urine albumin/creatinine ratio (UACR) of ≥30 mg/g or the presence of diabetic retinopathy (DR) assessed through mydriatic retinal imaging or ophthalmoscopy. Computer modeling, adjusted for age, sex, BMI, systolic blood pressure, smoking habits, glycated hemoglobin, the duration of diabetes, and antihypertensive treatment was used to estimate odd ratios (ORs) between sleep duration groups.
Findings
The study found that both short and long sleep durations were associated with an increased risk of microvascular disease compared to optimal sleep duration. Participants with short sleep duration had a 2.6 times increase in microvascular disease risk, while those with long sleep duration had a 2.3 times increase compared to optimal sleep duration. Further, the association between short sleep duration and microvascular disease was accentuated by age.
Interestingly, for participants aged under 62 years, short sleep duration only increased the risk of microvascular damage by 23% compared with optimal sleep duration. For those aged over 62 years, short sleep duration was associated with a 5.7 times increased risk of small blood vessel damage compared with optimal sleep duration.
Conclusion
While lifestyle changes, including sleep interventions, may potentially benefit individuals with type 2 diabetes, further studies are needed to determine the role of sleep duration and quality in these patients’ treatment. The findings of this study can contribute towards identifying modifiable risk factors that could prevent complications of type 2 diabetes, such as microvascular disease.
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Originally Post From https://www.news-medical.net/news/20240712/and-long-sleep-duration-linked-to-microvascular-disease-in-newly-diagnosed-diabetics.aspx
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